Burzlaff Group

2024

• Kraus A., Skoczynski K., Brötsch M., Burzlaff N., Leipziger J., Schiffer M., Büttner-Herold M., Buchholz B.:
  P2Y2R and Cyst Growth in Polycystic Kidney Disease.
  In: Journal of the American Society of Nephrology 35 (2024), p. 1351-1365
  ISSN: 1046-6673
  DOI: 10.1681/ASN.0000000000000416

2023

• Hartner A., Dambietz T., Cordasic N., Willam C., Burzlaff N., Brötsch M., Daniel C., Schiffer M., Amann KU., Veelken R., Schley G., Hilgers KF.:
  No benefit of HIF prolyl hydroxylase inhibition for hypertensive renal damage in renovascular hypertensive rats
  In: Frontiers in Physiology 14 (2023), Article No.: 1208105
  ISSN: 1664-042X
  DOI: 10.3389/fphys.2023.1208105

2022

• Pflock S., Langer F., Reil M., Strinitz L., Lorenz R., Hubner EG., Burzlaff N.:
  p-Block metal complexes with bis(pyrazol-1-yl)acetato ligands
  In: Dalton Transactions (2022)
  ISSN: 1477-9226
  DOI: 10.1039/d1dt04040e
• Tzegai W., Reil M., Burzlaff N.:
  Bis(4-carboxylpyrazol-1-yl)acetic acid: a scorpionate ligand for complexes with improved water solubility
  In: Dalton Transactions (2022)
  ISSN: 1477-9226
  DOI: 10.1039/d2dt00848c

2021

• Fuchs MA., Broeker KA., Schrankl J., Burzlaff N., Willam C., Wagner C., Kurtz A.:
  Inhibition of transforming growth factor β1 signaling in resident interstitial cells attenuates profibrotic gene expression and preserves erythropoietin production during experimental kidney fibrosis in mice
  In: Kidney International (2021)
  ISSN: 0085-2538
  DOI: 10.1016/j.kint.2021.02.035

2020

• Lopez S., Mayes DM., Crouzy SC., Cavazza C., Lepretre C., Moreau Y., Burzlaff N., Delapierre CM., Menage S.:
  A Mechanistic Rationale Approach Revealed the Unexpected Chemoselectivity of an Artificial Ru-Dependent Oxidase: A Dual Experimental/Theoretical Approach
  In: ACS Catalysis 10 (2020), p. 5631-5645
  ISSN: 2155-5435
  DOI: 10.1021/acscatal.9b04904
• Lorenz R., Reger D., Weller R., Jux N., Burzlaff N.:
  Hexa-: Peri-hexabenzocoronene decorated with an allenylidene ruthenium complex-Almost a flyswatter
  In: Dalton Transactions 49 (2020), p. 13134-13141
  ISSN: 1477-9226
  DOI: 10.1039/d0dt02729d

2019

• Schley G., Klanke B., Kalucka J., Schatz V., Daniel C., Mayer M., Goppelt-Strübe M., Herrmann M., Thorsteinsdottir M., Palsson R., Beneke A., Katschinski DM., Burzlaff N., Eckardt KU., Weidemann A., Jantsch J., Willam C.:
  Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis
  In: Kidney International (2019)
  ISSN: 0085-2538
  DOI: 10.1016/j.kint.2019.02.016

2018

• Anders HJ., Suarez-Alvarez B., Grigorescu M., Foresto-Neto O., Steiger S., Desai J., Marschner JA., Honarpisheh M., Shi C., Jordan J., Müller L., Burzlaff N., Bäuerle T., Mulay SR.:
  The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1-mediated tissue injury
  In: Kidney International 93 (2018), p. 656-669
  ISSN: 0085-2538
  DOI: 10.1016/j.kint.2017.09.022
• Beyer A., von Gernler M., Pflock S., Türkoglu G., Müller L., Zahl A., Gieb K., Müller P., Drewello T., Burzlaff N.:
  Alkali-Metal-Templated Self-Assembly of Nickel(II) [12-MC-3] Metallacoronates Based on Bis(pyrazol-1-yl)acetato Ligands
  In: Chemistry - A European Journal 2018 (2018), p. 765-777
  ISSN: 0947-6539
  DOI: 10.1002/ejic.201701400
• Fritsch N., Wick C., Waidmann T., Pflock S., Dral P., Tucher J., Steiner C., Shubina T., Maier S., Clark T., Burzlaff N.:
  1D Chains of Diruthenium Tetracarbonyl Sawhorse Complexes
  In: European Journal of Inorganic Chemistry (2018), p. 54-61
  ISSN: 1434-1948
  DOI: 10.1002/ejic.201701246
• Mayer M., Fey K., Heinze E., Wick C., Abboud MI., Yeh TL., Tumber A., Orth N., Schley G., Buchholz B., Clark T., Schofield CJ., Willam C., Burzlaff N.:
  A Fluorescent Benzo[g]isoquinoline-based HIF Prolyl Hydroxylase Inhibitor for Cellular Imaging.
  In: ChemMedChem 14 (2018), p. 94-99
  ISSN: 1860-7179
  DOI: 10.1002/cmdc.201800483

2017

• Schellinger IN., Cordasic N., Panesar J., Buchholz B., Jacobi J., Hartner A., Klanke B., Jakubiczka-Smorag J., Burzlaff N., Heinze E., Warnecke C., Raaz U., Willam C., Tsao PS., Eckardt KU., Amann KU., Hilgers KF.:
  Hypoxia inducible factor stabilization improves defective ischemia-induced angiogenesis in a rodent model of chronic kidney disease
  In: Kidney International 91 (2017), p. 616-627
  ISSN: 0085-2538
  DOI: 10.1016/j.kint.2016.09.028

2016

• Heim C., Bernhardt W., Jalilova S., Wang Z., Motsch B., Ramsperger-Gleixner M., Burzlaff N., Weyand M., Eckardt KU., Ensminger SM.:
  Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model
  In: Interactive Cardiovascular and Thoracic Surgery 22 (2016), p. 561-70
  ISSN: 1569-9293
  DOI: 10.1093/icvts/ivv352
• Heim C., Motsch B., Jalilova S., Bernhardt WM., Ramsperger-Gleixner M., Burzlaff N., Weyand M., Eckardt KU., Ensminger S.:
  Reduction of obliterative bronchiolitis (OB) by prolyl-hydroxylase-inhibitors activating hypoxia-inducible transcription factors in an experimental mouse model
  In: Transplant Immunology 39 (2016), p. 66-73
  ISSN: 0966-3274
  DOI: 10.1016/j.trim.2016.08.007
• Mulay SR., Eberhard JN., Desai J., Marschner JA., Kumar SV., Weidenbusch M., Grigorescu M., Lech M., Eltrich N., Müller L., Hans W., Hrabě de Angelis M., Vielhauer V., Hoppe B., Asplin J., Burzlaff N., Herrmann M., Evan A., Anders HJ.:
  Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease
  In: Journal of the American Society of Nephrology (2016)
  ISSN: 1046-6673
  DOI: 10.1681/ASN.2016040486
• Spörler S., Strinitz F., Rodehutskors PM., Müller L., Waterloo A., Dürr M., Hübner E., Ivanovic-Burmazovic I., Tykwinski R., Burzlaff N.:
  Carbon-rich cyclopentadienyl ruthenium allenylidene complexes
  In: New Journal of Chemistry 40 (2016), p. 6127-6134
  ISSN: 1144-0546
  DOI: 10.1039/c5nj03556b

2015

• Schley G., Scholz H., Kraus A., Hackenbeck T., Klanke B., Willam C., Wiesener M., Heinze E., Burzlaff N., Eckardt KU., Buchholz B.:
  Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis
  In: Kidney International 88 (2015), p. 1283-1292
  ISSN: 0085-2538
  DOI: 10.1038/ki.2015.214
• Schulz K., Hagos Y., Burckhardt G., Schley G., Burzlaff N., Willam C., Burckhardt BC.:
  The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3
  In: Nephron 131 (2015), p. 285-9
  ISSN: 0028-2766
  DOI: 10.1159/000442531
• Vogler M., Zieseniss A., Hesse AR., Levent E., Tiburcy M., Heinze E., Burzlaff N., Schley G., Eckardt KU., Willam C., Katschinski DM.:
  Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult
  In: Pflügers Archiv: European Journal of Physiology 467 (2015), p. 2141-9
  ISSN: 0031-6768
  DOI: 10.1007/s00424-014-1667-z

2014

• Fischer NV., Mitra U., Warnick KG., Dremov V., Stocker M., Wölfle T., Hieringer W., Heinemann FW., Burzlaff N., Görling A., Müller P.:
  High Resolution Scanning Tunneling Microscopy of a 1D Coordination Polymer with Imidazole-Based N,N,O Ligands on HOPG
  In: Chemistry - A European Journal 20 (2014), p. 11863-11869
  ISSN: 0947-6539
  DOI: 10.1002/chem.201302379
• Fritsch N., Wick C., Waidmann T., Dral P., Tucher J., Heinemann FW., Shubina T., Clark T., Burzlaff N.:
  Multiply Bonded Metal(II) Acetate (Rhodium, Ruthenium, and Molybdenum) Complexes with the trans-1,2-Bis(N-methylimidazol-2-yl)ethylene Ligand
  In: Inorganic Chemistry 53 (2014), p. 12305-12314
  ISSN: 0020-1669
  DOI: 10.1021/ic501435a
• Willam C., Eckhardt KU., Buchholz B., Schley G., Faria D., Kroening S., Willam C., Schreiber R., Klanke B., Burzlaff N., Jantsch J., Kunzelmann K., Eckardt KU.:
  Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion
  In: Journal of the American Society of Nephrology 25 (2014), p. 465-474
  ISSN: 1046-6673
  DOI: 10.1681/ASN.2013030209

2013

• Bleifuß S., Hofmann F., Burzlaff N.:
  An enantiopure N,N,O heteroscorpionate ligand derived from (-)-menthone
  In: Zeitschrift für Anorganische und Allgemeine Chemie 639 (2013), p. 1433-1437
  ISSN: 0044-2313
  DOI: 10.1002/zaac.201300085
• Strinitz F., Waterloo A., Tucher J., Huebner E., Tykwinski R., Burzlaff N.:
  Allenylidene complexes based on pentacenequinone
  In: European Journal of Inorganic Chemistry (2013), p. 5181-5186
  ISSN: 1434-1948
  DOI: 10.1002/ejic.201300759
• Tampier S., Bleifuß S., Abd-Elzaher MM., Sutter J., Heinemann FW., Burzlaff N.:
  Bis(pyrazol-1-yl)acetic acid bearing ferrocenyl substituents
  In: Organometallics 32 (2013), p. 5935-5945
  ISSN: 0276-7333
  DOI: 10.1021/om400495f
• Tampier S., Burzlaff N.:
  Heteroscorpionate complexes based on bis(3,5-di-tert-butylpyrazol-1-yl) dithioacetate
  In: Acta Crystallographica Section C: Crystal Structure Communications 69 (2013), p. 981-985
  ISSN: 0108-2701
  DOI: 10.1107/S0108270113021148
• Waidmann T., Fritsch N., Tucher J., Rudolf M., Glaser F., Guldi DM., Burzlaff N.:
  Battlement-shaped 1D coordination polymer based on a bis(N-methylimidazole- 2-yl)butadiyne ligand
  In: Crystengcomm 15 (2013), p. 10157-10160
  ISSN: 1466-8033
  DOI: 10.1039/c3ce41652f

2012

• Schley G., Klanke B., Schödel J., Kroening S., Türkoglu G., Beyer A., Hagos Y., Amann KU., Burckhardt BC., Burzlaff N., Eckardt KU., Willam C.:
  Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues
  In: American Journal of Pathology 181 (2012), p. 1595-1606
  ISSN: 0002-9440
  DOI: 10.1016/j.ajpath.2012.07.010
• Türkoglu G., Tampier S., Strinitz F., Heinemann FW., Huebner E., Burzlaff N.:
  Ruthenium carbonyl complexes bearing bis(pyrazol-1-yl)carboxylato ligands
  In: Organometallics 31 (2012), p. 2166-2174
  ISSN: 0276-7333
  DOI: 10.1021/om2009155
• Wang Z., Schley G., Türkoglu G., Burzlaff N., Amann KU., Willam C., Eckardt KU., Bernhardt WM.:
  The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
  In: Nephrology Dialysis Transplantation 27 (2012), p. 929-936
  ISSN: 0931-0509
  DOI: 10.1093/ndt/gfr379
• Wick C., Lanig H., Jäger C., Burzlaff N., Clark T.:
  Structural insight into the prolyl hydroxylase PHD2: A molecular dynamics and DFT study
  In: European Journal of Inorganic Chemistry (2012), p. 4973-4985
  ISSN: 1434-1948
  DOI: 10.1002/ejic.201200391

2011

• Fischer N., Alam S., Jum'H I., Stocker M., Fritsch N., Dremov V., Heinemann FW., Burzlaff N., Müller P.:
  Trans-1,2-bis(N-methylimidazol-2-yl)ethylene: Towards building blocks for 2D fabrics and MML-type 1D molecular strands
  In: Chemistry - A European Journal 17 (2011), p. 9293-9297
  ISSN: 0947-6539
  DOI: 10.1002/chem.201101053
• Godau T., Bleifuß S., Müller A., Roth T., Hoffmann S., Heinemann FW., Burzlaff N.:
  Cu(i) catalysed cyclopropanation with enantiopure scorpionate type ligands derived from (+)-camphor or (-)-menthone
  In: Dalton Transactions 40 (2011), p. 6547-6554
  ISSN: 1477-9226
  DOI: 10.1039/c1dt10032g
• Peters L., Tepedino F., Haas T., Heinemann FW., Wolf M., Burzlaff N.:
  Synthesis and transition metal complexes of 3,3-bis(1-vinylimidazol-2-yl) propionic acid, a new N,N,O ligand suitable for copolymerisation
  In: Inorganica Chimica Acta 374 (2011), p. 392-405
  ISSN: 0020-1693
  DOI: 10.1016/j.ica.2011.03.028
• Türkoglu G., Heinemann FW., Burzlaff N.:
  Transition metal complexes bearing a 2,2-bis(3,5-dimethylpyrazol-1-yl) propionate ligand: One methyl more matters
  In: Dalton Transactions 40 (2011), p. 4678-4686
  ISSN: 1477-9226
  DOI: 10.1039/c1dt00022e

2010

• Fischer N., Inayat A., Schwieger W., Burzlaff N.:
  Metal-organic frameworks constructed with 1, 2, 4-triazol-1-ylacrylic acid ligand: Syntheses and crystal structures
  In: Journal of Coordination Chemistry 63 (2010), p. 2831-2845
  ISSN: 0095-8972
  DOI: 10.1080/00958972.2010.506613
• Hübner E., Fischer N., Heinemann FW., Mitra U., Dremov V., Müller P., Burzlaff N.:
  N,N,O ligands based on triazoles and transition metal complexes thereof
  In: European Journal of Inorganic Chemistry (2010), p. 4100-4109
  ISSN: 1434-1948
  DOI: 10.1002/ejic.201000391
• Türkoglu G., Ulldemolins CP., Müller R., Hübner E., Heinemann FW., Wolf M., Burzlaff N.:
  Bis(3,5-dimethyl-4-vinylpyrazol-1-yl)acetic acid: A new heteroscorpionate building block for copolymers that mimic the 2-His-1-carboxylate facial triad
  In: European Journal of Inorganic Chemistry (2010), p. 2962-2974
  ISSN: 1434-1948
  DOI: 10.1002/ejic.2010015

2009

• Fischer N., Heinemann FW., Burzlaff N.:
  Two new imidazole-based heteroscorpionate ligands
  In: European Journal of Inorganic Chemistry (2009), p. 3960-3965
  ISSN: 1434-1948
  DOI: 10.1002/ejic.200900374
• Fischer N., Türkoglu G., Burzlaff N.:
  Scorpionate complexes suitable for enzyme inhibitor studies
  In: Current Bioactive Compounds 5 (2009), p. 277-295
  ISSN: 1573-4072
  DOI: 10.2174/157340709789816438
• Godau T., Platzmann F., Heinemann FW., Burzlaff N.:
  An enantiopure N,N,S scorpionate ligand derived from (+)-camphor
  In: Dalton Transactions (2009), p. 254-255
  ISSN: 1477-9226
  DOI: 10.1039/b819596j
• Peters L., Hübner E., Haas T., Heinemann FW., Burzlaff N.:
  3,3-Bis(3,5-dimethylpyrazol-1-yl)propionic acid: A tripodal N,N,O ligand for manganese and rhenium complexes - Syntheses and structures
  In: Journal of Organometallic Chemistry 694 (2009), p. 2319-2327
  ISSN: 0022-328X
  DOI: 10.1016/j.jorganchem.2009.03.037